While considerable research efforts have been made to explore the effective ways of teaching culture in second and foreign language settings, few studies have been carried out on the use of project-based instruction to promote language and culture learning. The purpose of the present study is twofold: to design a course using project-based instruction that would facilitate learning of language and culture as well as to investigate students' perceptions toward the project-based course. Thirty-four EFL college students in Taiwan participated in this study. Data regarding students' perceptions of the course were collected through a questionnaire as well as semistructured interviews. The results of the current study indicated that students in general had a positive attitude toward project-based instruction after participating in the course. Students viewed that project-based instruction had the advantages of offering opportunities for active learning, enhancing their English reading skills, and increasing their ability to use online resources. As for culture learning, students perceived that the project-based approach was particularly useful in learning cross-cultural topics and helped them gain more understanding toward other cultures. In spite of these advantages, the participants also reported several challenges associated with the course.